Product Name :
PDE4B Recombinant Rabbit Monoclonal Antibody [JE33-95]
Predicted band size :
83 kDa
Observed band size :
83 kDa
Synonyms:
5”-cyclic phosphodiesterase 4B antibody cAMP-specific 3” antibody cAMP-specific 3′,5′-cyclic phosphodiesterase 4B antibody cAMP-specific phosphodiesterase-4 B isoform antibody DKFZp686F2182 antibody DPDE4 antibody dunce-like phosphodiesterase E4 antibody MGC126529 antibody OTTHUMP00000010652 antibody OTTHUMP00000010653 antibody 展开
Function :
cAMP-specific 3′,5′-cyclic phosphodiesterase 4B is an enzyme that in humans is encoded by the PDE4B gene. This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant fragment within Human PDE4B aa 550 to the C-terminus.
Species reactivity:
Human, Mouse
Verify application:
WB, FC
Coupling :
unconjugated
Clone number:
JE33-95
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Price of AN-12-H5 intermediate-1 Aliquot store at -20℃.2,6-Pyridinedicarboxaldehyde In stock Avoid repeated freeze / thaw cycles.PMID:33682031
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 83 kDa
Positive control :
A549 cell lysate, human brain tissue lysate, mouse brain tissue lysate, mouse heart tissue lysate, A549.