Product Name :
SERCA2 Recombinant Rabbit Monoclonal Antibody [JM10-20]
Predicted band size :
115 kDa
Observed band size :
115 kDa
Synonyms:
AT2A2_HUMAN antibody Atp2a2 antibody ATP2B antibody ATPase Ca++ transporting cardiac muscle slow twitch 2 antibody Calcium pump 2 antibody Calcium-transporting ATPase sarcoplasmic reticulum type antibody Calcium-transporting ATPase sarcoplasmic reticulum type slow twitch skeletal muscle isoform antibody Cardiac Ca2+ ATPase antibody DAR antibody DD antibody 展开
Function :
ATP2A2 also known as sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) is an ATPase associated with Darier’s disease and Acrokeratosis verruciformis. This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human SERCA2 aa 999-1,042 / 1,042.6-Bromoquinoline-3-carbaldehyde In stock
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IF-Tissue, IHC-P, FC
Coupling :
unconjugated
Clone number:
JM10-20
RRID:
AB_3070359
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.39070-14-9 Purity Aliquot store at -20℃ or -80℃.PMID:33491520 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 115 kDa
Positive control :
A549 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, A549, Hela, MCF-7, human tonsil tissue, human kidney tissue, mouse skeletal muscle tissue, mouse skin tissue, human liver carcinoma tissue, mouse kidney tissue, mouse heart tissue.