Product Name :
TTC8 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
Bardet Biedl syndrome 8 protein Bardet Biedl syndrome type 8 Bardet-Biedl syndrome 8 protein BBS8 Tetratricopeptide repeat domain 8 Tetratricopeptide repeat protein 8 TPR repeat protein 8 TTC 8 Ttc8 TTC8_HUMAN.
Function :
The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.2′-Deoxy-2′-fluoroadenosine Data Sheet This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome.1,7-Naphthyridin-8(7H)-one manufacturer Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human BBS8 251-330/541
Species reactivity:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep
Verify application:
WB, ELISA, IHC-P, FC, IF, ICC
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.PMID:33733926 Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
61 KDa
Positive control :
Widely expressed.