Product Name :
Thymidine Phosphorylase Mouse Monoclonal Antibody [A1A10]
Predicted band size :
50 kDa
Observed band size :
50 kDa
Synonyms:
ECGF 1 antibody ECGF antibody ECGF1 antibody Endothelial cell growth factor 1 antibody Endothelial cell growth factor 1 platelet derived antibody Endothelial cell growth factor, platelet-derived antibody Gliostatin antibody hPD ECGF antibody MEDPS1 antibody MNGIE antibody 展开
Function :
Platelet-derived endothelial cell growth factor (PD-ECGF), which is alternatively designated thymidine phosphorylase or gliostatin, is an angiogenic inducer that potently stimulates the growth of endothelial cells and induces chemotaxis. Biologically active PD-ECGF is a functional dimer that consists of two single polypeptide chains that are expressed in platelets, placenta, foreskin fibroblasts and various squamous cell carcinomas, and they are slowly secreted from the cells. In addition, PD-ECGF is overexpressed in tumor and lesional psoriatic skin and lesional epidermis, indicating that it may play a role in the pathophysiology of psoriasis.5-(Thiazol-5-yl)nicotinic acid custom synthesis Serine residues of PD-ECGF are frequently associated with nucleotide triphosphates, including ATP.2-Iodobenzo[b]thiophene structure In an ATP dependent manner, PD-ECGF is also able to catalyze the reversible phosphorolysis of thymidine to thymine, as it contains thymidine phosphorylase activities.PMID:33590988
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Recombinant protein within Human Thymidine Phosphorylase aa 19-239 / 482.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P, FC, IF-Cell
Coupling :
unconjugated
Clone number:
A1A10
RRID:
AB_3068867
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG2a
Purification method :
Protein G affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 50 kDa
Positive control :
THP-1 cell lysate, A549 cell lysate, A431 cell lysate, HeLa cell lysate, human liver carcinoma tissue, human spleen tissue, SiHa, mouse spleen tissue, rat spleen tissue.