Product Name :
beta 2 Adrenergic Receptor Recombinant Rabbit Monoclonal Antibody [JM102-06]
Predicted band size :
46 kDa
Observed band size :
55-100 kDa
Synonyms:
ADRB2 antibody ADRB2_HUMAN antibody ADRB2R antibody ADRBR antibody Adrenergic beta 2 receptor surface antibody Adrenoceptor beta 2 surface antibody B2AR antibody BAR antibody beta 2 adrenoceptor antibody Beta 2 adrenoreceptor antibody 展开
Function :
The beta-2 adrenergic receptor (β2 adrenoreceptor), also known as ADRB2, is a cell membrane-spanning beta-adrenergic receptor that binds epinephrine (adrenaline), a hormone and neurotransmitter whose signaling, via adenylate cyclase stimulation through trimeric Gs proteins, increased cAMP, and downstream L-type calcium channel interaction, mediates physiologic responses such as smooth muscle relaxation and bronchodilation. The ADRB2 gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human ADRB2 aa 369-400 / 413.
Species reactivity:
Human, Mouse, Rat, Zebrafish
Verify application:
WB, IHC-P, IP, IF-Cell, FC
Coupling :
unconjugated
Clone number:
JM102-06
RRID:
AB_3070362
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.4-Methyloxazole Price Aliquot store at -20℃ or -80℃.528878-44-6 Data Sheet Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.PMID:33651728
ELTSA :
Molecular weight :
Predicted band size: 46 kDa
Positive control :
A431 cell lysate, human liver tissue lysate, mouse heart tissue lysate, rat heart tissue lysate, mouse kidney tissue lysate, rat kidney tissue lysate, zebrafish tissue lysates, A431, human liver tissue, human stomach tissue, mouse liver tissue, mouse stomach tissue, rat liver tissue, rat stomach tissue.