Product Name :
P450 1A2 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
Aryl hydrocarbon hydroxylase antibody CP 12 antibody CP12 antibody CP1A2_HUMAN antibody CYP1A2 antibody CYPIA2 antibody Cytochrome P(3)450 antibody Cytochrome P450 1A2 antibody Cytochrome P450 4 antibody Cytochrome P450 family 1 polypeptide 2 antibody 展开
Function :
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen.N-Fmoc-2,5-difluoro-L-phenylalanine custom synthesis Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human P450 1A2/CYP1A2 221-320/513
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, ELISA, IHC-P, FC, IF
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.C12-200 manufacturer Avoid repeated freeze/thaw cycles.PMID:33596787 The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
56 KDa
Positive control :
Liver.