Product Name :
PCBP1 Mouse Monoclonal Antibody [A3E10]
Predicted band size :
Observed band size :
Synonyms:
Alpha-CP1 antibody Heterogeneous nuclear ribonucleoprotein E1 antibody heterogenous nuclear ribonucleoprotein E1 antibody heterogenous nuclear ribonucleoprotein X antibody hnRNP E1 antibody hnRNP-E1 antibody hnRNP-X antibody HNRPE1 antibody HNRPX antibody nucleic acid binding protein sub 2.3 antibody 展开
Function :
This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP2 and HNRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5′-terminal cloverleaf structure.
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Recombinant protein within human PCBP1 aa 1-356.
Species reactivity:
Human, Mouse
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
A3E10
RRID:
AB_3071636
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
Store at +4℃ after thawing.4-Ethynyl-1,2-dimethylbenzene Chemscene Aliquot store at -20℃.Formula of Bis-PEG1-acid Avoid repeated freeze / thaw cycles.PMID:33723702
Storage buffer solution:
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG1
Purification method :
Protein G affinity purified.
ELTSA :
Molecular weight :
37 kDa
Positive control :
Hela cell lysate, K562 cell lysate, Human colon cancer tissue.