Product Name :
p50 dynamitin Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
50 kD dynein associated polypeptide antibody 50 kDa dynein associated polypeptide antibody 50 kDa dynein-associated polypeptide antibody DCTN-50 antibody DCTN2 antibody DCTN2_HUMAN antibody DCTN50 antibody dynactin 2 (p50) antibody dynactin 2 antibody dynactin complex 50 kD subunit antibody 展开
Function :
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 23 subunits (11 individual proteins ranging in size from 22 to 150 kD). The subunit is commonly referred to as p50 or dynamitin. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that bind to two copies of p150-glued (DCTN1) and two copies of p24 (DCTN3) to form the dynactin shoulder domain.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Recombinant protein within human p50 dynamitin aa 1-200.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IHC-P, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3071129
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.207591-86-4 In stock Aliquot store at -20℃.Price of Ir[dF(CF3)ppy]2(dtbbpy)PF6 Avoid repeated freeze / thaw cycles.PMID:33660564
Storage buffer solution:
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 44 kDa
Positive control :
SHSY5Y cell lysate, mouse brain tissue lysate, PANC-1, rat cerebellum tissue, SHSY5Y.